【論文】
Analysis of vitamin D receptor binding affinities of enzymatically synthesized
triterpenes including ambrein and unnatural onoceroids
Daijiro Ueda, Natsu Matsuda, Yuka Takaba, Nami Hirai, Mao Inoue, Taichi
Kameya, Tohru Abe, Nao Tagaya, Yasuhiro Isogai, Yoshito Kakihara, Florian
Bartels, Mathias Christmann, Tetsuro Shinada, Kaori Yasuda, Tsutomu SatoSci.
Rep., 14, 1419, 2024
Insight into the mechanism of geranyl-β-phellandrene formation catalyzed
by Class IB terpene synthases
Shogo Iwakata, Kazuya Asada, Tomoyuki Nishi, Rafaella Stepanova, So Shinoda,
Daijiro Ueda, Masahiro Fujihashi, Yoko Yasuno, Tetsuro Shinada, Tsutomu
Sato., Biosci. Biotechnol. Biochem., 86(6) 724-729 2022
Identification and functional analysis of a new type of Z,E-mixed prenyl reductase from mycobacteriaTohru Abe,Mariko Hakamata,Akihito Nishiyama,Yoshitaka Tateishi,Sohkichi Matsumoto,Hisashi Hemmi,Daijiro Ueda,Tsutomu Sato., FEBS J., 289(16), 2022
Construction of an artificial system for ambrein biosynthesis and investigation of some biological activities of ambrein. Yamabe Y., Kawagoe Y., Okuno K., Inoue M., Chikaoka K., Ueda D., Tajima Y., Yamada T.D., Kakihara Y., Hara T., Sato T., Sci. Rep., 10 19643 2020
Insight into Isoprenoid Biosynthesis by Functional Analysis of Isoprenyl Diphosphate Synthases from Mycobacterium vanbaalenii and Mycobacterium tuberculosis. Abe T, Ozaki S, Ueda D, Sato T Chembiochem : a European journal of chemical biology 21 2931-2938 2020
Molecular Basis for Sesterterpene (C25) Diversity Produced by Plant Terpene Synthases. Qingwen Chen, Jianxu Li, Zhixi Liu, Takaaki Mitsuhashi, Yuting Zhang, Haili Liu, Yihua Ma, Juan He, Tetsuro Shinada, Tsutomu Sato, Yong Wang, Hongwei Liu, Ikuro Abe, Peng Zhang,Guodong Wang.Plant communication 1 (5) 100051 2020
Characterization of Class IB terpene synthase: the first crystal structure bound with substrate surrogate. Stepanova Rafaella, Inagi Hayato, Sugawara Kei, Asada Kazuya, Nishi Tomoyuki, Ueda Daijiro, Yasuno Yoko, Shinada Tetsuro, Miki Kunio, Fujihashi Masahiro, Sato Tsutomu. ACS Chem. biol. 15 1517-1525 2020
Adduct Formation of Delamanid with NAD in Mycobacteria.Mikayo Hayashi, Akihito Nishiyama, Ryuki Kitamoto, Yoshitaka Tateishi, Mayuko Osada-Oka, Yukiko Nishiuchi, Shaban A. Kaboso, Xiuhao Chen, Mamoru Fujiwara, Yusuke Inoue, Yoshikazu Kawano, Masanori Kawasaki, Tohru Abe, Tsutomu Sato, Kentaro Kaneko, Kimiko Itoh, Sohkichi Matsumoto, Makoto Matsumoto. Antimicrobial Agents and Chemotherapy, 64(5) 1-12 2020
Japanese Rice Wine can reduce psychophysical stress-induced depression-like
behaviors and Fos expression in the trigeminal subnucleus caudalis evoked
by masseter muscle injury in the rats.
Nakatani Y, Kakihara Y, Shimizu S, Kurose M, Sato T, Kaneoke M, Saeki M,
Takagi R, Yamamura K, Okamoto K
Bioscience, Biotechnology, and Biochemistry 83(1) 155- 165 2019
An Aromatic Farnesyltransferase Functions in Biosynthesis of the Anti-HIV
Meroterpenoid Daurichromenic Acid.
Saeki H, Hara R, Takahashi H, Iijima M, Munakata R, Kenmoku H, Fuku K,
Sekihara A, Yasuno Y, Shinada T, Ueda D, Nishi T, Sato T, Asakawa Y, Kurosaki
F, Yazaki K, Taura F
Plant physiology 178(2) 535 - 551 2018
A Non-Enzymatic Pathway with Superoxide in Intracellular Terpenoid Synthesis.
Ueda D, Matsugane S, Okamoto W, Hashimoto M, Sato T
Angewandte Chemie (International ed. in English) 57(32) 10347 - 10351 2018
Crystal structure and functional analysis of large-terpene synthases belonging
to a newly found subclass.
Fujihashi M, Sato T, Tanaka Y, Yamamoto D, Nishi T, Ueda D, Murakami M,
Yasuno Y, Sekihara A, Fuku K, Shinada T, Miki K
Chemical science 9(15) 3754 - 3758 2018
Bioinspired synthesis of pentacyclic onocerane triterpenoids.
Bartels F, Hong YJ, Ueda D, Weber M, Sato T, Tantillo DJ, Christmann M
Chemical science 8(12) 8285 - 8290 2017
Analysis of the Catalytic Mechanism of Bifunctional Triterpene/Sesquarterpene
Cyclase: Tyr167 Functions To Terminate Cyclization of Squalene at the Bicyclic
Step.
Tenkovskaia L, Murakami M, Okuno K, Ueda D, Sato T
Chembiochem : a European journal of chemical biology 18(19) 1910 - 1913
2017
Biosynthesis of Sesterterpenes, Head-to-Tail Triterpenes, and Sesquarterpenes
in Bacillus clausii: Identification of Multifunctional Enzymes and Analysis of Isoprenoid
Metabolites.
Ueda D, Yamaga H, Murakami M, Totsuka Y, Shinada T, Sato T
Chembiochem : a European journal of chemical biology 16(9) 1371 - 1377
2015
Cyclization of squalene from both termini: identification of an onoceroid
synthase and enzymatic synthesis of ambrein.
Ueda D, Hoshino T, Sato T
Journal of the American Chemical Society 135(49) 18335 - 18338 2013
Enzymatic syntheses of unnatural head-to-tail pentacyclic triterpenes by
tetraprenyl-beta-curcumene cyclase
Okamoto Wataru, Sato Tsutomu
TETRAHEDRON LETTERS 54(49) 6747 - 6750 2013
Identification of novel sesterterpene/triterpene synthase from Bacillus clausii.
Sato T, Yamaga H, Kashima S, Murata Y, Shinada T, Nakano C, Hoshino T
Chembiochem : a European journal of chemical biology 14(7) 822 - 825 2013
Insight into the pathway for biosynthesis of sesquarterpenes in nonpathogenic
Mycobacterium species: identification of heptaprenylcycli-14E,18E-diene
Sato Tsutomu, Ono Eri, Nakajima Mami, Nakano Chiaki, Hoshino Tsutomu
TETRAHEDRON LETTERS 53(20) 2522 - 2524 2012
Bifunctional triterpene/sesquarterpene cyclase: tetraprenyl-β-curcumene
cyclase is also squalene cyclase in Bacillus megaterium.
Sato T, Hoshino H, Yoshida S, Nakajima M, Hoshino T
Journal of the American Chemical Society 133(44) 17540 - 17543 2011
Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene
cyclase: identification of a new terpene cyclase.
Sato T, Yoshida S, Hoshino H, Tanno M, Nakajima M, Hoshino T
Journal of the American Chemical Society 133(25) 9734 - 9737 2011
Insight into C35 terpene biosyntheses by nonpathogenic Mycobacterium Species: functional analyses of three Z-prenyltransferases and identification
of dehydroheptaprenylcyclines.
Sato T, Takizawa K, Orito Y, Kudo H, Hoshino T
Chembiochem : a European journal of chemical biology 11(13) 1874 - 1881
2010
Novel compounds of octahydroheptaprenyl mycolic acyl ester and monocyclic
C35-terpene, heptaprenylcycline B, from non-pathogenic mycobacteriumspecies.
Sato T, Takagi R, Orito Y, Ono E, Hoshino T
Bioscience, biotechnology, and biochemistry 74(1) 147 - 151 2010
Biosynthesis of a novel cyclic C35-terpene via the cyclisation of a Z-type
C35-polyprenyl diphosphate obtained from a nonpathogenic Mycobacterium species.
Sato T, Kigawa A, Takagi R, Adachi T, Hoshino T
Organic & biomolecular chemistry 6(20) 3788 - 3794 2008
【総説・解説】
龍涎香の人工合成系の確立に向けてー新規アンブレイン合成酵素の創出ー
化学と生物，59(5), 222-224(2021).
佐藤努
龍涎香主成分アンブレインの人工生合成経路の創出と確立
バイオサイエンスとインダストリー，79 (3)224-225 (2021).
上田大次郎, 佐藤努
龍涎香主成分アンブレイン合成酵素の開発とアンブレインの生物活性解析
アロマリサーチ，22 (2), 109-115(2021).
上田大次郎, 佐藤努
龍涎香に関する研究
上田大次郎, 佐藤努
季刊香料 (273) 53‐59 2017年3月20日
龍涎香に関する研究
上田 大次郎, 佐藤 努
香料 (273) 53 - 59 2017
龍涎香の主成分アンブレインの酵素合成
上田大次郎, 星野力, 佐藤努
Aroma Res 16(2) 142 - 143 2015
龍涎香の主成分アンブレインの酵素合成
上田大次郎, 星野力, 佐藤努
バイオサイエンスとインダストリー 72(5) 410 - 411 2014
Unique biosynthesis of sesquarterpenes (C35 terpenes).
Sato T
Bioscience, biotechnology, and biochemistry 77(6) 1155 - 1159 2013
ユニークなセスクアテルペン(C35テルペン)生合成経路 : 今までに類のない新型と二機能性テルペン環化酵素の同定
佐藤 努
化学と生物 50(9) 622 - 623 2012
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